杜笙樹脂 有４種關于制藥業(yè)配方的應用。
TULSION® resins find a number of applications as Excipients in Pharmaceutical Formulations .

應用 / Applications

杜笙樹脂于藥品的應用大致可以分為以下４大類別 :
The use in pharmaceutical formulations can be classified under one of the following four categories

<味道包覆劑> – 一些藥物含有苦味 ,可用杜笙交換樹脂來吸收此苦味而相對比較沒苦味。人的口中及胃的酸堿值 （pH）大約是在相同的范圍 ,因此藥品不會在口中溶解而只在胃里溶解。因此,當藥經(jīng)過口中時 ,藥品的結構仍處于錯化物，沒有任何的味道被釋出。不同的樹脂選擇來包含苦味,取決于藥品特性 （請連絡我們以取得更詳細資料）。
<Taste Masking Agent> – Certain drugs that have a very bitter taste can be made relatively tase  y adsorbing the drugs on Tulsion Exchange Resins . The pH in the mouth being on the basic side compared to the pH in the stomach , the complex drug will not be released in the mouth but only in the stomach. Since while passing through the mouth the drug remains in the complex form , none or very little taste is imparted. The nature of resin used is dependent upon the type of drug being masked （please contact us for more details）.

<藥片溶解劑> - 為了確保一旦藥片攝入，能提供所需的藥物。一樣的藥片劑，一樣的迅速溶解是可以達到的。外用試劑添加到藥片配方，以確保藥片溶解。TULSION®樹脂可 被當成是藥劑溶解劑。這是由于樹脂會比樹脂處于氫﹑鉀的 “Polacrilin鉀” 樹脂的形式容易膨脹，因而成為在這個應用程序的*形式樹脂。
<Tablet Disintegrant> – In order to ensure that once a tablet is ingested , the desired drug is delivered . It is desirable that the tablet disintegrates uniformly and quickly. External agents are added to a tablet formulation to ensure the disintegration. TULSION® resins ca be used as a disintegrating agent. This is due to the fact that the resin will swell than the resin in hydrogen form , Potassium form of the resin “Polacrilin Potassium” is preferred in this applications.


<藥效持續(xù)釋放> -緩釋劑是要確保藥物不斷的 ,慢慢的，但穩(wěn)定的速度被釋放到身體。藥劑從離子交換樹脂釋放是取決于身體內不同液體與藥品及樹脂錯化物之間的反應來決定。對藥物的釋放速度可通過改變控 制粒子的大小，樹脂交聯(lián)的程度及樹脂的化學性質。此種持續(xù)性的釋放藥效配方是可以依照不同的應用而量身訂作的。
<Sustained Release> – Sustained release formulations ensure that the drug is released continuously into the body at a slower , but steady rate. The release of durgs from ion exchange resins depends upon a series of ionic reactio  etween various body fluids and drug – resin complex . The rate of release of drugs can be controlled by varying the particle size , degree of cross-linking and the chemistry of resin. The release profile can almost be tailor made to suit a particular application.

<藥效穩(wěn)定藥物> - 例如藥物，* – 12的存儲時，經(jīng)過一段時間會慢慢分解。此類藥物的穩(wěn)定可藉由使用TULSION®樹脂來達成。
<Drug Stabilization> – Drugs for instance, Vitamin B-12 when stored , degenerate after some time. The stabilization of such drugs can be brought about using Tulsion resins.

TULSION®杜笙樹脂是經(jīng)過美國藥品管理局認證通過 ，并具有 ISO 9001 及ISO 14001 的品質認證。

FDA Approved  ISO 9001 : 2000  ISO 14001
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